Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 3/20 | 0.39 |
| ▸ | GABRD | O14764 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.39 |
| ▸ | GABRE | P78334 | 3/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200703 | 0.83 | KDM4E (0.41) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL27554928 | 0.81 | KDM4E (0.40) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL438266 | 0.79 | KMT2A (0.47) | KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL25999705 | 0.77 | KDM4E (0.36) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL438745 | 0.75 | KEAP1 (0.49) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL438931 | 0.75 | HAVCR2 (0.49) | KDM4EASPHKDM8GABRPGABRD | |
| SCHEMBL437520 | 0.73 | AAK1 (0.34) | BCHEACHE | |
| SCHEMBL439299 | 0.73 | BCHE (0.34) | KMT2ABCHEACHECA1CA2 | |
| SCHEMBL2712583 | 0.73 | BCHE (0.39) | BCHEACHEMAP4K4 | |
| SCHEMBL440033 | 0.72 | KEAP1 (0.49) | KMT2AKEAP1HAVCR2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |