Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 3/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355881 | 0.88 | FOLH1 (0.41) | TSHRFAAHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25355885 | 0.88 | FOLH1 (0.41) | TSHRFAAHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1619320 | 0.87 | TSHR (0.43) | TSHRFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL18412629 | 0.83 | ALDH1A1 (0.55) | TSHRFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL19646650 | 0.82 | FOLH1 (0.44) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21964558 | 0.82 | ALDH1A1 (0.39) | TSHRFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL8477259 | 0.82 | ALDH1A1 (0.39) | TSHRFAAHALDH1A1MEN1KMT2A | |
| SCHEMBL21964560 | 0.82 | FOLH1 (0.44) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13124556 | 0.82 | MEN1 (0.59) | FAAHALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25968884 | 0.82 | MEN1 (0.59) | FAAHALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263900-A1 | DENDRIMER-DRUG CONJUGATE | STARPHARMA PTY LTD (AU) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263900-A1 | DENDRIMER-DRUG CONJUGATE | SARS1, MMAB, PAM | TSHR 2979/4885FAAH 2384/4885ALDH1A1 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.