Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCR | P30988 | 4/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.58 |
| ▸ | TFPI | P10646 | 2/20 | 0.56 |
| ▸ | NPY2R | P49146 | 2/20 | 0.56 |
| ▸ | NPY4R | P50391 | 2/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26003156 | 1.00 | CALCR (0.61) | CALCROPRD1TFPINPY2RNPY4R | |
| SCHEMBL26003281 | 0.97 | CALCR (0.58) | CALCROPRD1TFPI | |
| SCHEMBL30358154 | 0.90 | CALCR (0.64) | CALCROPRD1NPY2RNPY4RNPY5R | |
| SCHEMBL29867671 | 0.89 | F2 (0.62) | CALCRTFPINPY2RNPY4RNPY5R | |
| SCHEMBL30497011 | 0.88 | OPRD1 (0.67) | CALCROPRD1TFPI | |
| SCHEMBL30432005 | 0.87 | CALCR (0.62) | CALCRTFPINPY2RNPY4RNPY5R | |
| SCHEMBL29610214 | 0.87 | CALCR (0.62) | CALCROPRD1TFPINPY2RNPY4R | |
| SCHEMBL31005079 | 0.87 | TFPI (0.67) | CALCROPRD1TFPINPY2RNPY4R | |
| SCHEMBL30262116 | 0.87 | F2 (0.62) | CALCROPRD1TFPINPY2RNPY4R | |
| SCHEMBL31182439 | 0.86 | CALCR (0.63) | CALCROPRD1NPY2RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263800-A1 | COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION | FRED HUTCHINSON CANCER CENTER (US) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263800-A1 | COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION | BMP4, P2RY2, GPR39 | CALCR 28/4885OPRD1 2931/4885TFPI 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.