Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25952563 | 0.93 | PAOX (0.50) | GNAI3GNAO1GNAI1HTR7HTR1A | |
| SCHEMBL24352087 | 0.90 | GNAI3 (0.49) | GNAI3GNAO1GNAI1HTR7HTR1A | |
| SCHEMBL27342066 | 0.87 | NPC1 (0.53) | GNAI3GNAO1GNAI1HTR7HTR1A | |
| SCHEMBL24352368 | 0.86 | GNAI3 (0.45) | GNAI3GNAO1GNAI1HTR7HTR1A | |
| SCHEMBL26042836 | 0.85 | ALDH1A1 (0.49) | GNAI3GNAO1GNAI1HTR7HTR1A | |
| SCHEMBL24204316 | 0.83 | L3MBTL3 (0.47) | GNAI3GNAO1GNAI1HTR7HTR1A | |
| SCHEMBL26005384 | 0.80 | GNAI3 (0.60) | GNAI3GNAO1GNAI1L3MBTL3L3MBTL1 | |
| SCHEMBL24352085 | 0.80 | HSD11B1 (0.50) | GNAI3GNAO1GNAI1HTR7HTR1A | |
| SCHEMBL24204659 | 0.79 | GNAI3 (0.48) | GNAI3GNAO1GNAI1L3MBTL3L3MBTL1 | |
| SCHEMBL24351548 | 0.78 | L3MBTL3 (0.43) | GNAI3GNAO1GNAI1HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268052-A9 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |