SCHEMBL2601427

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2601428	0.83	ALDH1A1 (0.49)	KEAP1MEN1KMT2AMIFTHRB
	SCHEMBL12998131	0.75	MIF (0.42)	MEN1KMT2ASMN1; SMN2MIFMAPT
	SCHEMBL19593463	0.75	ALDH1A1 (0.41)	KEAP1MEN1KMT2ASMN1; SMN2NPC1
	SCHEMBL10446873	0.72	MIF (0.42)	MEN1KMT2AMIFMAOBAKR1B1
	SCHEMBL22261555	0.72	MIF (0.42)	MEN1KMT2AMIFMAOBAKR1B1
	SCHEMBL2601487	0.72	MIF (0.42)	MEN1KMT2AMIFMAOBAKR1B1
	SCHEMBL21183649	0.72	MIF (0.42)	MEN1KMT2AMIFTP53MAOB
	SCHEMBL18796296	0.72	MAOB (0.49)	MEN1KMT2AMIFMAPTMAOB
	SCHEMBL4819056	0.71	KEAP1 (0.54)	KEAP1MEN1KMT2ASMN1; SMN2NPC1
	SCHEMBL2601430	0.70	PIM1 (0.44)	MEN1KMT2AMIFMAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.