Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD1 | P21728 | 4/20 | 0.35 |
| ▸ | DRD5 | P21918 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340105 | 0.83 | KDM4E (0.38) | KDM4ECHRNA7DRD2DRD1DRD5 | |
| SCHEMBL26017354 | 0.83 | CHEK1 (0.37) | KDM4ECHRNA7DRD2DRD1DRD5 | |
| SCHEMBL24101581 | 0.83 | KDM4E (0.38) | KDM4ECHRNA7DRD2DRD1DRD5 | |
| SCHEMBL26017449 | 0.83 | DRD2 (0.44) | HTR6KDM4ECHRNA7DRD2DRD1 | |
| SCHEMBL26017341 | 0.81 | USP2 (0.48) | KDM4ECHRNA7DRD2DRD1DRD5 | |
| SCHEMBL26017450 | 0.76 | PRKCB (0.37) | HTR6KDM4EDRD2DRD1DRD5 | |
| SCHEMBL3715595 | 0.74 | L3MBTL1 (0.57) | HTR6HTR1AHTR2CHTR7KDM4E | |
| SCHEMBL21588364 | 0.74 | NISCH (0.43) | HTR7KDM4ECYP1A2CYP2D6PMP22 | |
| SCHEMBL24101593 | 0.74 | KDM4E (0.47) | HTR6KDM4ECHRNA7DRD2DRD1 | |
| SCHEMBL30063679 | 0.74 | KDM4E (0.47) | HTR6KDM4ECHRNA7DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122135-A1 | SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME | KULEON LLC (US) | 2023-06-29 | — | — | WO | disclosed |