Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.44 |
| ▸ | DRD1 | P21728 | 8/20 | 0.44 |
| ▸ | DRD5 | P21918 | 8/20 | 0.44 |
| ▸ | DRD3 | P35462 | 8/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26017356 | 0.83 | HTR6 (0.36) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL24101581 | 0.83 | KDM4E (0.38) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL30340105 | 0.83 | KDM4E (0.38) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL26017354 | 0.83 | CHEK1 (0.37) | DRD2DRD1DRD5DRD3CHEK1 | |
| SCHEMBL26017341 | 0.81 | USP2 (0.48) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL26017450 | 0.78 | PRKCB (0.37) | DRD2DRD1DRD5DRD3CHEK1 | |
| SCHEMBL3715595 | 0.74 | L3MBTL1 (0.57) | DRD2DRD3KDM4ECHRNA7CYP1A2 | |
| SCHEMBL24101593 | 0.74 | KDM4E (0.47) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL30063679 | 0.74 | KDM4E (0.47) | DRD2DRD1DRD5DRD3KDM4E | |
| SCHEMBL12480316 | 0.73 | CHRNA7 (0.50) | KDM4ECHRNA7CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122135-A1 | SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME | KULEON LLC (US) | 2023-06-29 | — | — | WO | disclosed |