Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 12/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 2/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21387271 | 0.78 | PARP1 (0.50) | SERPINE1PARP1KDM4ETNKSPARP15 | |
| SCHEMBL31047679 | 0.76 | SERPINE1 (0.65) | SERPINE1PARP1KDM4ETNKSPARP15 | |
| SCHEMBL29914858 | 0.75 | MEN1 (0.47) | SERPINE1PARP1KDM4ETNKSPARP15 | |
| SCHEMBL30364598 | 0.74 | ALDH1A1 (0.50) | PARP1KDM4ETNKSPARP15TNKS2 | |
| SCHEMBL3081936 | 0.71 | PARP1 (0.71) | SERPINE1PARP1KDM4ETNKSPARP15 | |
| SCHEMBL5017370 | 0.71 | SERPINE1 (0.55) | SERPINE1PARP1TNKSTNKS2MAPT | |
| SCHEMBL31175987 | 0.68 | KDM4E (0.53) | PARP1KDM4ETNKSPARP15TNKS2 | |
| SCHEMBL147819 | 0.65 | MAOA (0.58) | ALDH1A1LMNACYP1A2BLMPMP22 | |
| SCHEMBL29440644 | 0.65 | MAOA (0.58) | ALDH1A1LMNACYP1A2BLMPMP22 | |
| SCHEMBL31014307 | 0.64 | SERPINE1 (0.71) | SERPINE1PARP1KDM4ETNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |