Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KDM1A | O60341 | 6/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725782 | 0.86 | ITGB2 (0.59) | KMT2AMEN1KDM1APIM1LMNA | |
| SCHEMBL29628227 | 0.86 | ITGB2 (0.59) | KMT2AMEN1KDM1APIM1LMNA | |
| SCHEMBL24039977 | 0.81 | KDM1A (0.54) | KMT2AMEN1KDM1APIM1LMNA | |
| SCHEMBL21436177 | 0.78 | MEN1 (0.50) | KMT2AMEN1KDM1APTGS1PTGS2 | |
| SCHEMBL9382075 | 0.74 | TSHR (0.56) | KMT2AMEN1LMNAMAOAMAOB | |
| SCHEMBL1581710 | 0.72 | KDM1A (0.53) | KMT2AMEN1KDM1APTGS1PTGS2 | |
| SCHEMBL9077379 | 0.72 | PTGS1 (0.58) | KMT2AMEN1KDM1APTGS1PTGS2 | |
| SCHEMBL29557425 | 0.72 | KDM1A (0.61) | KMT2AKDM1APTGS1PTGS2PIM1 | |
| SCHEMBL10690359 | 0.72 | PIM1 (0.63) | KMT2AMEN1KDM1APTGS1PTGS2 | |
| SCHEMBL293951 | 0.72 | KDM1A (0.61) | KMT2AKDM1APTGS1PTGS2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10406227-B2 | Photoactivated molecules for light-induced modulation of the activity of electrically excitable cells and methods of using same | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-09-10 | — | — | US | disclosed |
| EP-3027229-B1 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME | UNIV SOUTHERN CALIFORNIA (US) | 2019-07-17 | — | — | EP | disclosed |
| US-10232043-B2 | Photoactivated molecules for light-induced modulation of the activity of electrically excitable cells and methods of using the same | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-03-19 | — | — | US | disclosed |
| US-20170189530-A1 | PHOTOACTIVATED MOLECULES FOR LIGHT INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING THE SAME | UNIVERSITY OF SOUTHERN CALIFORNIA | 2017-07-06 | — | — | US | disclosed |
| WO-2017031380-A1 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-02-23 | — | — | WO | disclosed |
| EP-3027229-A1 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME | University of Southern California (US) | 2016-06-08 | — | — | EP | disclosed |
| US-20150328313-A1 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME | UNIVERSITY OF SOUTHERN CALIFORNIA | 2015-11-19 | — | — | US | disclosed |
| WO-2014100283-A1 | PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-06-26 | — | — | WO | disclosed |
| US-20120100628-A1 | EMISSIVE AND BROADBAND NONLINEAR ABSORBING METAL COMPLEXES AND LIGANDS AS OLED, OPTICAL SWITCHING OR OPTICAL SENSING MATERIALS | NDSU RESEARCH FOUNDATION (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100628-A1 | EMISSIVE AND BROADBAND NONLINEAR ABSORBING METAL COMPLEXES AND LIGANDS AS OLED, OPTICAL SWITCHING OR OPTICAL SENSING MATERIALS | NDSU RESEARCH FOUNDATION (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100628-A1 | EMISSIVE AND BROADBAND NONLINEAR ABSORBING METAL COMPLEXES AND LIGANDS AS OLED, OPTICAL SWITCHING OR OPTICAL SENSING MATERIALS | OCIAD2, OCIAD1, NONO | KMT2A 2880/4885MEN1 1678/4885KDM1A 4438/4885 |
| US-10406227-B2 | Photoactivated molecules for light-induced modulation of the activity of electrically excitable cells and methods of using same | TRPM8, TRPM2, TRPM4 | KMT2A 3627/4885MEN1 2398/4885KDM1A 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.