Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.34 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725124 | 0.83 | ACMSD (0.40) | SSTR4ACMSDCYP2C9NOTUMALDH1A1 | |
| SCHEMBL1725857 | 0.81 | ACMSD (0.53) | ACMSDNOTUMRXRBMAPTDHODH | |
| SCHEMBL26020416 | 0.80 | POLQ (0.46) | ACMSDCYP2C9ADORA2ADHODHACLY | |
| SCHEMBL1726032 | 0.77 | KDM4E (0.46) | SSTR4ALDH1A1LMNAMAPT | |
| SCHEMBL4909993 | 0.76 | SMN1; SMN2 (0.52) | LMNAMAPTDHODHHDAC8HDAC6 | |
| SCHEMBL20503247 | 0.75 | ACMSD (0.58) | ACMSDNOTUMRXRBDHODHHDAC8 | |
| SCHEMBL13544502 | 0.75 | ACMSD (0.63) | ACMSDNOTUMDHODHHDAC8HDAC6 | |
| SCHEMBL11988898 | 0.74 | NFE2L2 (0.45) | RXRBHSD11B1 | |
| SCHEMBL17679285 | 0.73 | PTGDR2 (0.40) | ADORA2ALMNAHSD11B1 | |
| SCHEMBL20503312 | 0.73 | ACMSD (0.64) | ACMSDNOTUMDHODHHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257382-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257382-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TRPC5, TRPC1, GOT1 | SSTR4 1088/4885ACMSD 2191/4885CYP2C9 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.