SCHEMBL26021847

SCHEMBL26021847

c1ccc(-c2ccc3cc(Nc4ccc(-c5cc6ccccc6c6ccccc56)c5ccccc45)ccc3c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
MAPT P10636 3/20 0.40
MAPK14 Q16539 2/20 0.40
ALK Q9UM73 1/20 0.38
CDC25B P30305 2/20 0.37
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
TP53 P04637 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
ATM Q13315 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26021778 0.89 CDC25B (0.46) ALDH1A1CYP3A4HPGDHSD17B10MAPT
SCHEMBL13903709 0.85 ALDH1A1 (0.45) ALDH1A1CYP3A4HPGDHSD17B10MAPT
SCHEMBL26034207 0.84 ESR1 (0.43) ALDH1A1CYP3A4HPGDHSD17B10MAPT
SCHEMBL26021869 0.83 MAPT (0.53) ALDH1A1CYP3A4HPGDHSD17B10MAPT
SCHEMBL24545362 0.83 ALDH1A1 (0.46) ALDH1A1CYP3A4HPGDHSD17B10MAPT
SCHEMBL25932541 0.83 ALDH1A1 (0.49) ALDH1A1CYP3A4HPGDHSD17B10MAPT
SCHEMBL17740697 0.83 ALDH1A1 (0.53) ALDH1A1CYP3A4HPGDHSD17B10MAPT
SCHEMBL12476447 0.81 ALDH1A1 (0.59) ALDH1A1CYP3A4HPGDHSD17B10MAPT
SCHEMBL27287243 0.81 CDC25B (0.46) ALDH1A1CYP3A4HPGDHSD17B10MAPT
SCHEMBL26021822 0.81 ALDH1A1 (0.51) ALDH1A1CYP3A4HPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242498-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-08-03 US disclosed
US-20230242498-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242498-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, NR1D1 ALDH1A1 90/4885CYP3A4 762/4885HPGD 2944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.