⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26022703 | 0.79 | — | — | |
| SCHEMBL26022755 | 0.75 | — | — | |
| SCHEMBL26022754 | 0.75 | CYP2D6 (0.31) | — | |
| SCHEMBL26032473 | 0.73 | — | — | |
| SCHEMBL26022700 | 0.69 | LMNA (0.31) | — | |
| SCHEMBL22596444 | 0.68 | NOS3 (0.34) | — | |
| SCHEMBL6616471 | 0.68 | HTR2C (0.44) | — | |
| SCHEMBL26022693 | 0.66 | NOS1 (0.48) | — | |
| SCHEMBL13955039 | 0.66 | NOS1 (0.43) | — | |
| SCHEMBL26022752 | 0.63 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265096-A1 | APOL1 INHIBITORS AND METHODS OF USE | HERCULES CAPITAL, INC., AS AGENT | 2023-08-24 | — | — | US | disclosed |