Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21731047 | 0.79 | KDM4E (0.39) | CYP1A2CYP2C19SMN1; SMN2KDM4EHTT | |
| SCHEMBL27724755 | 0.78 | GAA (0.46) | TDP1L3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL25974302 | 0.76 | FFAR1 (0.46) | TDP1L3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL25345554 | 0.75 | ENPP2 (0.39) | TDP1L3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29380731 | 0.75 | ALDH1A1 (0.42) | TDP1L3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1030557 | 0.75 | ALDH1A1 (0.42) | TDP1L3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL26024874 | 0.75 | L3MBTL1 (0.38) | TDP1L3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23148080 | 0.74 | ALDH1A1 (0.53) | L3MBTL1SMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL14402360 | 0.74 | HPGD (0.47) | TDP1L3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL26023956 | 0.73 | L3MBTL1 (0.46) | TDP1L3MBTL1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |