SCHEMBL26026065

SCHEMBL26026065

NCC1CCCC(C(=O)O)=N1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLG P00747 1/20 0.34
PLAT P00750 1/20 0.34
LMNA P02545 1/20 0.34
OAT P04181 1/20 0.34
NOS1 P29475 4/20 0.33
NOS2 P35228 4/20 0.33
NOS3 P29474 3/20 0.33
CYP2D6 P10635 1/20 0.33
GABRR1 P24046 4/20 0.31
GABRR2 P28476 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17281364 0.71 NOS3 (0.47) OATNOS1NOS2NOS3
SCHEMBL1939017 0.62 NAPRT (0.41) LMNANOS1NOS2
SCHEMBL28768420 0.61 GABRP (0.35) GABRR1
Bicarbonate SCHEMBL15519847 0.59 CYP2D6 (0.63) PLGPLATLMNACYP2D6GABRR1
Bicarbonate SCHEMBL31059126 0.59 GABRR1 (0.48) PLGPLATLMNACYP2D6GABRR1
SCHEMBL9373328 0.59 NOS1 (0.47) NOS1NOS2NOS3GABRR1
Bicarbonate SCHEMBL25270175 0.58 PLG (0.71) PLGPLATLMNACYP2D6GABRR1
SCHEMBL142379 0.57
SCHEMBL9835844 0.57
Decarboxylated Derivative SCHEMBL2813888 0.57 CYP2D6 (0.67) PLGPLATLMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3318555-B1 BIFUNCTIONAL CHELATING AGENTS BWXT MEDICAL LTD (CA) 2023-08-16 EP disclosed