Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541633 | 0.84 | PPARA (0.40) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL19658184 | 0.83 | TDP1 (0.42) | PSMB8PSMB5F2RL1 | |
| SCHEMBL7453768 | 0.82 | F2RL1 (0.53) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL112099 | 0.80 | FAAH (0.41) | KMT2AHPGDMEN1ALDH1A1TSHR | |
| SCHEMBL9752036 | 0.79 | L3MBTL1 (0.43) | KMT2ASMN1; SMN2ALDH1A1TSHRPSMB8 | |
| SCHEMBL13920679 | 0.79 | FFAR1 (0.42) | KMT2AMEN1ALDH1A1PSMB8PSMB5 | |
| SCHEMBL8948701 | 0.79 | PSMB8 (0.37) | PSMB8PSMB5 | |
| SCHEMBL13939391 | 0.77 | F2RL1 (0.45) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL13939438 | 0.76 | F2RL1 (0.44) | KMT2ASMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL6193414 | 0.76 | MGLL (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445612-B2 | Conjugation reactions | BIOCOMPATIBLES UK LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-8445612-B2 | Conjugation reactions | BIOCOMPATIBLES UK LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-8431113-B2 | Polymer conjugates | BIOCOMPATIBLES UK LIMITED (GB) | 2013-04-30 | — | — | US | disclosed |
| US-8431113-B2 | Polymer conjugates | BIOCOMPATIBLES UK LIMITED (GB) | 2013-04-30 | — | — | US | disclosed |
| US-20120016082-A1 | CONJUGATION REACTIONS | BIOCOMPATIBLES UK LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-20120016082-A1 | CONJUGATION REACTIONS | BIOCOMPATIBLES UK LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-20120016085-A1 | POLYMER CONJUGATES | BIOCOMPATIBLES UK LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-20120016085-A1 | POLYMER CONJUGATES | BIOCOMPATIBLES UK LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-8053520-B2 | Conjugation reactions | BIOCOMPATIBLES UK LIMITED (GB) | 2011-11-08 | — | — | US | disclosed |
| US-8053520-B2 | Conjugation reactions | BIOCOMPATIBLES UK LIMITED (GB) | 2011-11-08 | — | — | US | disclosed |
| US-8048408-B2 | addition polymerization of zwitterionic monomers, under molecular weight control, to form polymers having low polydispersity, used for drug delivery | BIOCOMPATIBLES UK LIMITED (GB) | 2011-11-01 | — | — | US | disclosed |
| US-8048408-B2 | addition polymerization of zwitterionic monomers, under molecular weight control, to form polymers having low polydispersity, used for drug delivery | BIOCOMPATIBLES UK LIMITED (GB) | 2011-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016082-A1 | CONJUGATION REACTIONS | PHPT1, GNE, MGMT | ELANE 1334/4885KMT2A 900/4885SMN1; SMN2 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.