SCHEMBL6450325

SCHEMBL6450325

O=C(O)c1c(O)c(O)c(O)c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 4/20 0.50
PDE10A Q9Y233 1/20 0.50
HPGD P15428 3/20 0.48
HSD17B10 Q99714 3/20 0.48
THRB P10828 1/20 0.48
CYP2C9 P11712 1/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
ATIC P31939 1/20 0.48
KDM4E B2RXH2 3/20 0.48
MEN1 O00255 2/20 0.48
ALDH1A1 P00352 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP1A2 P05177 1/20 0.48
GLA P06280 1/20 0.48
CYP2C19 P33261 1/20 0.48
LDHA P00338 6/20 0.47
LDHB P07195 4/20 0.47
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31039922 1.00 DHODH (0.50) DHODHPDE10AHPGDHSD17B10THRB
SCHEMBL29260803 0.93 DHODH (0.55) DHODHPDE10AHPGDHSD17B10THRB
SCHEMBL901598 0.91 HSD17B10 (0.48) DHODHPDE10AHPGDHSD17B10THRB
SCHEMBL28261469 0.88 DHODH (0.52) DHODHPDE10AHPGDHSD17B10THRB
SCHEMBL344711 0.88 HSD17B10 (0.50) DHODHPDE10AHPGDHSD17B10THRB
SCHEMBL2477681 0.86 HSD17B10 (0.58) DHODHPDE10AHPGDHSD17B10THRB
SCHEMBL7537511 0.84 DHODH (0.52) DHODHPDE10AHPGDHSD17B10THRB
SCHEMBL31414101 0.83 HSD17B10 (0.54) DHODHPDE10AHPGDHSD17B10THRB
SCHEMBL4415520 0.83 HSD17B10 (0.54) DHODHPDE10AHPGDHSD17B10THRB
SCHEMBL27572021 0.82 HSD17B10 (0.48) DHODHPDE10AHPGDHSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230296984-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20230296984-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20210397090-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION AND METHOD FOR FORMING RESIST PATTERN USING THE SAME NISSAN CHEMICAL CORPORATION (JP) 2021-12-23 US disclosed
US-10336859-B2 Method for preparing an electrolyte capacitor TAYCA CORPORATION (JP) 2019-07-02 US disclosed
US-20190106531-A1 Method for preparing an electrolyte capacitor TAYCA CORPORATION (JP) 2019-04-11 US disclosed
US-9589738-B2 Solid electrolyte capacitor and a method for manufacturing the same TAYCA CORPORATION (JP) 2017-03-07 US disclosed
US-20140334066-A1 SOLID ELECTROLYTE CAPACITOR AND A METHOD FOR MANUFACTURING THE SAME TAYCA CORPORATION (JP) 2014-11-13 US disclosed
US-20050228038-A1 11-Beta hydroxysteroid dehydrogenase type 1 inhibitors as anti-obesity/anti-diabetes compounds and 17-beta hydrosteroid dehydrogenase type I inhibitors as useful agents for the treatment of cancers, especially breast cancer SCIENCE & TECHNOLOGY CORPORATION @ UNM 2005-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050228038-A1 11-Beta hydroxysteroid dehydrogenase type 1 inhibitors as anti-obesity/anti-diabetes compounds and 17-beta hydrosteroid dehydrogenase type I inhibitors as useful agents for the treatment of cancers, especially breast cancer HSD17B1, HSD11B1, HSD17B2 DHODH 39/4885PDE10A 4297/4885HPGD 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.