Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269710 | 0.82 | KEAP1 (0.58) | FFAR1KEAP1ALDH1A1HDAC1MAOB | |
| SCHEMBL185769 | 0.78 | SLC6A2 (0.50) | CES1ALDH1A1MAOBMAOA | |
| Bromide SCHEMBL28214530 | 0.76 | SLC6A2 (0.48) | CES1ALDH1A1MAOBMAOA | |
| Water SCHEMBL28298252 | 0.76 | SLC6A2 (0.48) | CES1ALDH1A1MAOBMAOA | |
| Ammonia Solution, Strong SCHEMBL29253660 | 0.76 | SLC6A2 (0.48) | CES1ALDH1A1MAOBMAOA | |
| SCHEMBL5694881 | 0.74 | TDP1 (0.54) | FFAR1KEAP1ALDH1A1HDAC1MAOB | |
| Hydrochloric Acid SCHEMBL29076224 | 0.74 | SLC6A2 (0.46) | CES1ALDH1A1MAOBMAOA | |
| SCHEMBL20973256 | 0.73 | CES1 (0.49) | FFAR1KEAP1CES1FAAHALDH1A1 | |
| Methylamine SCHEMBL28065528 | 0.72 | TAAR1 (0.56) | CES1MAOBMAOA | |
| SCHEMBL28877320 | 0.72 | KEAP1 (0.47) | FFAR1KEAP1CES1FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397638-B1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2023-08-23 | — | — | EP | disclosed |