Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877320 | 0.86 | KEAP1 (0.47) | CES1FAAHKEAP1POLBGAA | |
| SCHEMBL31402809 | 0.82 | MAOB (0.44) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL16155161 | 0.82 | ESR1 (0.50) | POLBGAAALDH1A1TDP1HDAC2 | |
| SCHEMBL27616806 | 0.79 | ALDH1A1 (0.50) | KEAP1POLBALDH1A1FFAR1TDP1 | |
| SCHEMBL28112171 | 0.78 | CES1 (0.57) | CES1FAAHALDH1A1HDAC8HDAC6 | |
| SCHEMBL31402818 | 0.78 | TAAR1 (0.49) | FFAR1 | |
| SCHEMBL31402812 | 0.76 | F2RL1 (0.53) | POLBGAAALDH1A1FFAR1SMN1; SMN2 | |
| SCHEMBL12195215 | 0.76 | KEAP1 (0.54) | KEAP1ALDH1A1FFAR1TDP1HDAC2 | |
| SCHEMBL1274684 | 0.75 | CES1 (0.73) | CES1FAAHKEAP1ALDH1A1FFAR1 | |
| SCHEMBL3247318 | 0.75 | CES1 (0.49) | CES1FAAHKEAP1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530110-A | Gem-difluoro bicyclo [2.1.1] hexane carboxylic acid compound | 南京工业大学 | 2024-08-23 | — | — | CN | disclosed |
| CN-118530110-A | Gem-difluoro bicyclo [2.1.1] hexane carboxylic acid compound | 南京工业大学 | 2024-08-23 | — | — | CN | disclosed |
| US-20190144469-A1 | METHOD FOR PREPARING DIFLUOROALLYLBORONATE AND APPLICATION THEREOF | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2019-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144469-A1 | METHOD FOR PREPARING DIFLUOROALLYLBORONATE AND APPLICATION THEREOF | GABRA6, GABRP, GABBR2 | CES1 3239/4885FAAH 690/4885KEAP1 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.