SCHEMBL26029328

SCHEMBL26029328

CCC(=O)OCc1ccc(NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CCC(C)C)C(C)C)cc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 2/20 0.43
▸ KLKB1 P03952 1/20 0.43
▸ MMP3 P08254 1/20 0.42
▸ SIRT2 Q8IXJ6 7/20 0.42
▸ SIRT1 Q96EB6 6/20 0.42
▸ CALCRL Q16602 1/20 0.42
▸ CPB1 P15086 1/20 0.41
▸ CPB2 Q96IY4 1/20 0.41
▸ PDF Q9HBH1 1/20 0.41
▸ SSTR3 P32745 1/20 0.41
▸ SIRT3 Q9NTG7 3/20 0.40
▸ HDAC4 P56524 1/20 0.39
▸ MEF2D Q14814 1/20 0.39
▸ SIRT5 Q9NXA8 1/20 0.39
▸ PLG P00747 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26017200 0.91 MMP3 (0.43) FURINKLKB1MMP3SIRT2SIRT1
SCHEMBL26017207 0.91 MMP3 (0.43) FURINKLKB1MMP3SIRT2SIRT1
SCHEMBL26192867 0.91 MMP3 (0.43) FURINKLKB1MMP3SIRT2SIRT1
SCHEMBL22420225 0.90 SIRT2 (0.44) FURINSIRT2SIRT1SIRT3SIRT5
SCHEMBL26033422 0.89 SIRT1 (0.45) FURINKLKB1MMP3SIRT2SIRT1
SCHEMBL26257608 0.87 SIRT2 (0.43) FURINSIRT2SIRT1SIRT3
SCHEMBL24591816 0.86 SIRT2 (0.44) FURINSIRT2SIRT1SIRT3SIRT5
SCHEMBL24390289 0.85 SIRT1 (0.45) FURINKLKB1MMP3SIRT2SIRT1
SCHEMBL24906651 0.85 SIRT1 (0.45) FURINKLKB1MMP3SIRT2SIRT1
SCHEMBL26033430 0.85 SIRT1 (0.45) FURINKLKB1MMP3SIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744897-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof ELUCIDA ONCOLOGY, INC. (US) 2023-09-05 — — US disclosed
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR FURIN 2202/4885KLKB1 2964/4885MMP3 2647/4885
US-11744897-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof FOLR1, FOLR2, DHFR FURIN 2202/4885KLKB1 2964/4885MMP3 2647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback