SCHEMBL26030187

SCHEMBL26030187

CCc1cc(Cc2cc(CC)c(C)c(CC)c2Cl)cc(C)c1C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DHFR P00374 2/20 0.34
SHBG P04278 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26030188 0.86 ALDH1A1 (0.33)
SCHEMBL25765756 0.82 DHFR (0.38) DHFRSHBG
SCHEMBL13964544 0.80 ALDH1A1 (0.33)
SCHEMBL24152554 0.74 DHFR (0.33) DHFR
SCHEMBL166178 0.73 DHFR (0.42) DHFR
SCHEMBL25765759 0.70 DHFR (0.33) DHFR
SCHEMBL31208456 0.70 ALDH1A1 (0.34)
SCHEMBL17373679 0.68 NOS3 (0.34)
SCHEMBL31122964 0.68 GRIN2D (0.35)
SCHEMBL14597274 0.67 SCN4A (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265287-A1 NOVEL COMPOSITIONS WITH IMPROVED CHARACTERISTICS Arxada Switzerland AG (CH) 2023-08-24 US disclosed