SCHEMBL26030188

SCHEMBL26030188

CCc1cc(Cc2cc(CC)c(C)c(CC)c2Cl)c(Cl)c(CC)c1C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13964544 0.93 ALDH1A1 (0.33) ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL26030187 0.86 DHFR (0.34)
SCHEMBL25765759 0.82 DHFR (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31208456 0.81 ALDH1A1 (0.34) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL31122964 0.79 GRIN2D (0.35) CYP1A2CYP2D6CYP2C9CYP2C19RXFP1
SCHEMBL15262 0.77 HTT (0.38) ALDH1A1CYP1A2
SCHEMBL5141186 0.77
SCHEMBL9344581 0.77 ALDH1A1 (0.32) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3675876 0.75 ALDH1A1 (0.35) ALDH1A1CYP1A2
SCHEMBL10341228 0.75 ALDH1A1 (0.39) ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265287-A1 NOVEL COMPOSITIONS WITH IMPROVED CHARACTERISTICS Arxada Switzerland AG (CH) 2023-08-24 US disclosed