Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25975795 | 0.83 | POLB (0.34) | RAB9ASLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL22993438 | 0.82 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP2D6ALDH1A1 | |
| SCHEMBL26032297 | 0.75 | — | — | |
| SCHEMBL25924943 | 0.73 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1DPP8DPP9 | |
| SCHEMBL20883859 | 0.73 | MEN1 (0.47) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL13453039 | 0.73 | MEN1 (0.47) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL19406887 | 0.70 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6KMT2A | |
| SCHEMBL1952271 | 0.69 | LMNA (0.33) | RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL109930 | 0.68 | MAPT (0.40) | AKR1C3RAB9AADRB2CYP2D6MEN1 | |
| SCHEMBL5986119 | 0.67 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |