Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26032155 | 0.83 | AKR1C3 (0.33) | MEN1KMT2ASIGMAR1ALDH1A1SLC6A2 | |
| SCHEMBL22993438 | 0.79 | SLC6A2 (0.40) | SMN1; SMN2ALDH1A1KDM4ESLC6A2SLC6A4 | |
| SCHEMBL17409800 | 0.79 | POLB (0.42) | POLBMEN1KMT2AATMSMN1; SMN2 | |
| SCHEMBL26032293 | 0.76 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL13102586 | 0.74 | POLB (0.53) | POLBMEN1KMT2AATMDRD2 | |
| SCHEMBL25975998 | 0.71 | POLB (0.46) | POLBMEN1KMT2AATMSMN1; SMN2 | |
| SCHEMBL25924943 | 0.71 | ALDH1A1 (0.34) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7657781 | 0.70 | LMNA (0.32) | KDM4EMAPT | |
| SCHEMBL21377311 | 0.69 | MAPT (0.36) | POLBMEN1KMT2AATMSMN1; SMN2 | |
| SCHEMBL24478558 | 0.69 | SLC6A2 (0.34) | SMN1; SMN2ALDH1A1KDM4ESLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |