Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19406887 | 0.78 | SLC6A2 (0.39) | ALDH1A1LMNAKMT2APOLBTSHR | |
| SCHEMBL13961198 | 0.73 | DPP8 (0.45) | ALDH1A1MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL26032155 | 0.73 | AKR1C3 (0.33) | ALDH1A1MEN1KMT2ADPP8DPP9 | |
| SCHEMBL25924944 | 0.73 | L3MBTL3 (0.36) | — | |
| SCHEMBL25925007 | 0.72 | HTR2C (0.36) | — | |
| SCHEMBL25975795 | 0.71 | POLB (0.34) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL6369707 | 0.68 | HRH3 (0.51) | MEN1KMT2APOLB | |
| SCHEMBL6369524 | 0.68 | HRH3 (0.51) | MEN1KMT2APOLB | |
| SCHEMBL22993438 | 0.67 | SLC6A2 (0.40) | ALDH1A1MAPTHTTDPP8DPP9 | |
| SCHEMBL23569863 | 0.66 | KDM1A (0.40) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |