⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25851551 | 0.91 | — | — | |
| SCHEMBL26034228 | 0.81 | — | — | |
| SCHEMBL25851494 | 0.72 | CCR2 (0.32) | — | |
| SCHEMBL26259196 | 0.70 | — | — | |
| SCHEMBL25856815 | 0.69 | CCR2 (0.36) | — | |
| SCHEMBL24340622 | 0.68 | TDP1 (0.31) | — | |
| SCHEMBL24340877 | 0.66 | — | — | |
| SCHEMBL22361334 | 0.66 | ALDH1A1 (0.31) | — | |
| SCHEMBL25790926 | 0.65 | TP53 (0.35) | — | |
| SCHEMBL23169030 | 0.65 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265429-A1 | SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF | Arrowhead Pharmaceuticals, Inc. | 2023-08-24 | — | — | US | disclosed |