Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23169030 | 0.80 | TSHR (0.33) | SMN1; SMN2ALDH1A1HPGDCNR1GAA | |
| SCHEMBL22923593 | 0.77 | MEN1 (0.41) | KMT2AHPGDCNR1MEN1 | |
| SCHEMBL25851494 | 0.75 | CCR2 (0.32) | ALDH1A1 | |
| SCHEMBL24855536 | 0.75 | ALDH1A1 (0.33) | TP53SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL24264728 | 0.74 | TP53 (0.31) | TP53SMN1; SMN2HPGDGAA | |
| SCHEMBL24920323 | 0.74 | — | — | |
| SCHEMBL22923591 | 0.74 | CASP2 (0.41) | SMN1; SMN2KMT2AALDH1A1HPGDCNR1 | |
| SCHEMBL24709963 | 0.73 | TP53 (0.41) | TP53SMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL25791933 | 0.72 | KDM4E (0.32) | ALDH1A1CNR1 | |
| SCHEMBL24654075 | 0.72 | PTGS1 (0.39) | TP53SMN1; SMN2KMT2AALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |