Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26034705 | 0.86 | THRB (0.34) | LPOTHRBTSHRALDH1A1POLB | |
| SCHEMBL24205119 | 0.83 | TSHR (0.45) | LPOTHRBTSHRPOLBAPEX1 | |
| SCHEMBL26034717 | 0.82 | LPO (0.40) | LPOTHRBTSHRALDH1A1POLB | |
| SCHEMBL26034700 | 0.78 | HSD17B13 (0.35) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL26034449 | 0.78 | TSHR (0.45) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL831448 | 0.74 | TSHR (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL24205092 | 0.74 | TSHR (0.43) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL26034715 | 0.73 | DUT (0.36) | TSHRALDH1A1POLBAPEX1HTT | |
| SCHEMBL25368674 | 0.73 | TSHR (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL26034452 | 0.72 | TSHR (0.46) | LPOTHRBTSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | LPO 252/4885THRB 4667/4885TSHR 4592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.