SCHEMBL831448

SCHEMBL831448

C=C(C)C(=O)OCn1c(=O)n(COC(=O)C(=C)C)c(=O)n(COC(=O)C(=C)C)c1=O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
ALDH1A1 P00352 5/20 0.46
THRB P10828 1/20 0.44
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KMT2A Q03164 2/20 0.34
ATM Q13315 1/20 0.34
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
BLM P54132 1/20 0.31
WRN Q14191 1/20 0.31
HIF1A Q16665 1/20 0.31
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL830644 0.89 TSHR (0.43) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL21657539 0.88 THRB (0.40) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL18927855 0.88 POLB (0.40) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL150780 0.82 THRB (0.48) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL28004954 0.81 TSHR (0.43) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL4185493 0.80 TSHR (0.42) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL19117376 0.79 POLB (0.34) TSHRALDH1A1THRBPOLB
SCHEMBL278374 0.79 TSHR (0.53) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL8747653 0.78 ALDH1A1 (0.56) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL1263149 0.77 TSHR (0.56) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1636274-B1 PHOTOCURABLE RESIN COMPOSITION DSM IP ASSETS BV (NL) 2009-08-12 EP claimed
US-20070096355-A1 Photocurable resin composition YASHIRO TAKAO 2007-05-03 US claimed
EP-1636274-A1 PHOTOCURABLE RESIN COMPOSITION DSM IP Assets B.V. (NL) 2006-03-22 EP claimed
WO-2004113395-A1 PHOTOCURABLE RESIN COMPOSITION DSM IP ASSETS B.V. (NL) 2004-12-29 WO claimed
US-11424482-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEMICAL CORPORATION (JP) 2022-08-23 US disclosed
US-11296357-B2 Non-aqueous electrolytic solution and non-aqueous electrolyte secondary battery using the same MITSUBISHI CHEMICAL CORPORATION (JP) 2022-04-05 US disclosed
US-20210020991-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2021-01-21 US disclosed
US-10615455-B2 Non-aqueous electrolytic solution and non-aqueous electrolyte secondary battery using the same MITSUBISHI CHEMICAL CORPORATION (JP) 2020-04-07 US disclosed
US-20200036041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2020-01-30 US disclosed
US-20190334208-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2019-10-31 US disclosed
US-10428214-B2 Cationically curable resin composition THREEBOND CO., LTD. (JP) 2019-10-01 US disclosed
US-10424812-B2 Non-aqueous electrolytic solution and non-aqueous electrolyte secondary battery using the same MITSUBISHI CHEMICAL CORPORATION (JP) 2019-09-24 US disclosed
EP-1577090-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-21 EP disclosed
WO-2004113395-A1 PHOTOCURABLE RESIN COMPOSITION DSM IP ASSETS B.V. (NL) 2004-12-29 WO disclosed
US-20020028287-A1 Manufacture of optical fiber and optical fiber tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-03-07 US disclosed
EP-1182178-A1 Manufacture of optical fiber and optical fiber tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-02-27 EP disclosed
EP-0478794-B2 PHOTOCURABLE RESIN JAPAN INST ADVANCED DENTISTRY (JP) 2001-02-28 EP disclosed
EP-0478794-B1 PHOTOCURABLE RESIN JAPAN INST ADVANCED DENTISTRY (JP) 1995-11-29 EP disclosed
US-5308886-A Bisphenol ether acrylates JAPAN INSTITUTE OF ADVANCED DENTISTRY (JP) 1994-05-03 US disclosed
EP-0478794-A1 PHOTOCURABLE RESIN JAPAN INSTITUTE OF ADVANCED DENTISTRY (JP) 1992-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210020991-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY SLC9B2, SLC9A1, SLC9A2 TSHR 4689/4885ALDH1A1 3675/4885THRB 3916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.