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SCHEMBL26035877

SCHEMBL26035877

CC1CC(=O)N(CCC(=O)NCCOCCOCCC(=O)N[C@@H](CCC(=O)NCC(C)(C)COCC(C)(C)CNC(=O)C(C)(C)CCC(C)(C)C)C(=O)NCC(C)(C)COCC(C)(C)CNC(=O)C(C)(C)CCC(C)(C)C)C1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 2/20 0.33
▸ GLP1R P43220 8/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26035646 0.89 — —
SCHEMBL26035509 0.79 OPRK1 (0.31) OPRK1
SCHEMBL26035729 0.78 — —
SCHEMBL25838416 0.76 GLP1R (0.33) OPRK1GLP1R
SCHEMBL13659676 0.75 GLP1R (0.39) OPRK1GLP1R
SCHEMBL26036030 0.75 — —
SCHEMBL27382245 0.75 GLP1R (0.34) GLP1R
SCHEMBL25840225 0.74 GLP1R (0.32) GLP1R
SCHEMBL19343049 0.73 SMN1; SMN2 (0.42) —
SCHEMBL16870946 0.73 SMN1; SMN2 (0.42) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 OPRK1 1136/4885GLP1R 1683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.