SCHEMBL25838416

SCHEMBL25838416

CCCNC(=O)CCC(NC(=O)CCOCCOCCNC(=O)CCN1C(=O)CC(C)C1=O)C(=O)NCC(C)COCC(C)(C)CC=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.33
OPRK1 P41145 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19703885 0.76 SMN1; SMN2 (0.38)
SCHEMBL20414123 0.76 SMN1; SMN2 (0.38)
SCHEMBL26035877 0.76 OPRK1 (0.33) GLP1ROPRK1
SCHEMBL24658634 0.73 CYP2C19 (0.33) OPRK1
SCHEMBL26032070 0.71 GLP1R (0.52) GLP1ROPRK1
SCHEMBL26032035 0.71 GLP1R (0.52) GLP1ROPRK1
SCHEMBL26032037 0.71 GLP1R (0.52) GLP1ROPRK1
SCHEMBL26032096 0.71 GLP1R (0.48) GLP1ROPRK1
SCHEMBL19703449 0.71 SMN1; SMN2 (0.37)
SCHEMBL19703635 0.71 SMN1; SMN2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 GLP1R 1985/4885OPRK1 2884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.