Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457286 | 0.94 | ALDH1A1 (0.48) | MMP12ALDH1A1MMP2MMP1MMP9 | |
| SCHEMBL12885598 | 0.91 | MAOB (0.57) | ALDH1A1NPC1RAB9AMAOBPARP10 | |
| SCHEMBL15762727 | 0.87 | ALDH1A1 (0.48) | ALDH1A1POLBMEN1KMT2ACA1 | |
| SCHEMBL12885597 | 0.86 | RAB9A (0.45) | MMP12ALDH1A1MMP2MMP1MMP9 | |
| SCHEMBL8085256 | 0.86 | RAB9A (0.53) | ALDH1A1NPC1RAB9AAGXTNAAA | |
| SCHEMBL25454006 | 0.85 | MAPT (0.47) | MMP12ALDH1A1MMP2MMP1MMP9 | |
| SCHEMBL14464460 | 0.85 | MAOB (0.62) | ALDH1A1NPC1RAB9AMAOBPARP10 | |
| SCHEMBL260469 | 0.83 | MMP12 (0.42) | MMP12ALDH1A1MMP2MMP1MMP9 | |
| SCHEMBL9687590 | 0.81 | ALDH1A1 (0.60) | MMP12ALDH1A1MMP2MMP1MMP9 | |
| SCHEMBL9686517 | 0.81 | ALDH1A1 (0.60) | MMP12ALDH1A1MMP2MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067440-B2 | Phosphonium salts derivatives and uses thereof | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-11-29 | — | — | US | disclosed |
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | PI4K2A, PIP4K2A, PI4K2B | MMP12 4651/4885ALDH1A1 3468/4885MMP2 1227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.