SCHEMBL26037495

SCHEMBL26037495

CCCCCCCCC(CCCCCC)C(=O)NCC(C)(C)COCC(C)(C)CNC(=O)CC[C@H](NC(=O)CC(C)OCC(C)CNC(=O)CCN1C(=O)C=CC1=O)C(=O)NCC(C)(C)COCC(C)(C)CNC(=O)C(CCCCCC)CCCCCCCC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25840350 0.82 GLP1R (0.33) GLP1R
SCHEMBL25840353 0.81 GLP1R (0.42) GLP1R
SCHEMBL27382530 0.81 GLP1R (0.43) GLP1R
SCHEMBL25845185 0.76 AKT1 (0.35)
SCHEMBL26259231 0.74 AKT1 (0.37) GLP1R
SCHEMBL26036004 0.72 BIRC2 (0.39) GLP1R
SCHEMBL26035192 0.69 GLP1R (0.40) GLP1R
SCHEMBL26035269 0.68 GLP1R (0.35) GLP1R
SCHEMBL25839706 0.67 AKT1 (0.33)
SCHEMBL18893551 0.67 SIRT6 (0.50) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 GLP1R 1683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.