Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 1/20 | 0.34 |
| ▸ | RGS8 | P57771 | 1/20 | 0.34 |
| ▸ | LGMN | Q99538 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LPO | P22079 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24665501 | 0.80 | ALDH1A1 (0.39) | RGS4RGS8ALDH1A1PDE4AADORA2A | |
| SCHEMBL8876423 | 0.68 | KDM4E (0.42) | ALDH1A1ADORA2AADORA2BGAAHTT | |
| SCHEMBL24205178 | 0.65 | MAPK1 (0.45) | ALDH1A1 | |
| SCHEMBL25980045 | 0.65 | LMNA (0.46) | ALDH1A1PDE4AADORA2BPDE4BPDE4C | |
| SCHEMBL26124117 | 0.64 | BRD4 (0.36) | ALDH1A1LPOADORA2BGAAHTT | |
| SCHEMBL15125556 | 0.64 | DRD2 (0.43) | ALDH1A1PDE4AADORA2AADORA2BPDE4B | |
| SCHEMBL27506471 | 0.63 | POLB (0.39) | ALDH1A1GAAHTTGSK3AGSK3B | |
| SCHEMBL11718868 | 0.62 | BRD4 (0.38) | ALDH1A1PDE4AADORA2AADORA2BPDE4B | |
| SCHEMBL24665500 | 0.61 | HSD17B13 (0.44) | ALDH1A1 | |
| SCHEMBL22511362 | 0.61 | MPO (0.37) | ALDH1A1PDE4AADORA2AADORA2BPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | RGS4 2355/4885RGS8 3467/4885LGMN 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.