Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26042003 | 0.81 | VDR (0.36) | VDRSKP2HRH4SLC6A3 | |
| SCHEMBL17304240 | 0.76 | HTR2C (0.33) | SIGMAR1PRKCQ | |
| SCHEMBL23762991 | 0.72 | CA12 (0.41) | SIGMAR1PRKCQ | |
| SCHEMBL26039913 | 0.69 | HTR2C (0.40) | VDRSKP2 | |
| SCHEMBL18536009 | 0.68 | SKP2 (0.50) | VDRSKP2 | |
| SCHEMBL24328529 | 0.67 | HTR1D (0.39) | — | |
| SCHEMBL2881923 | 0.66 | SIGMAR1 (0.50) | SIGMAR1PRKCQ | |
| SCHEMBL833088 | 0.64 | SKP2 (0.47) | VDRSKP2 | |
| SCHEMBL26041148 | 0.63 | VDR (0.33) | VDRSKP2 | |
| SCHEMBL17304320 | 0.63 | LRRK2 (0.40) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150592-B1 | ALK KINASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | SHANGHAI EMERALD WELLCARES PHARMACEUTICAL CO LTD (CN) | 2023-08-30 | — | — | EP | disclosed |