Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328529 | 0.86 | HTR1D (0.39) | HTR1DHTR1BNOS3NOS1HTR1F | |
| SCHEMBL26039913 | 0.82 | HTR2C (0.40) | VDRSKP2 | |
| SCHEMBL26040679 | 0.81 | VDR (0.34) | VDRSKP2SLC6A3HRH4 | |
| SCHEMBL18698318 | 0.74 | QDPR (0.45) | HTR1DHTR1BHTR1FALOX15DRD2 | |
| SCHEMBL13548512 | 0.74 | HTR1D (0.40) | HTR1DHTR1BTLR7HTR1FALOX15 | |
| SCHEMBL30640846 | 0.72 | ALK (0.43) | HTR1DHTR1BHTR1F | |
| SCHEMBL17304106 | 0.72 | ALK (0.43) | HTR1DHTR1BHTR1F | |
| SCHEMBL18536009 | 0.72 | SKP2 (0.50) | VDRSKP2ALOX15 | |
| SCHEMBL12635462 | 0.71 | QDPR (0.44) | HTR1DHTR1BHTR1FDRD2 | |
| SCHEMBL12705449 | 0.69 | HTR1D (0.35) | HTR1DHTR1BTLR7HTR1FALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150592-B1 | ALK KINASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | SHANGHAI EMERALD WELLCARES PHARMACEUTICAL CO LTD (CN) | 2023-08-30 | — | — | EP | disclosed |