SCHEMBL26041279

SCHEMBL26041279

CC(C)(C)c1cccc2c1C(=O)c1cccc(N(C(C)(C)C)C(C)(C)C)c1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.47
MAPT P10636 5/20 0.47
ALDH1A1 P00352 5/20 0.47
MAPK1 P28482 4/20 0.47
TDP1 Q9NUW8 4/20 0.47
EGFR P00533 2/20 0.47
LMNA P02545 2/20 0.47
NSD2 O96028 1/20 0.47
PABPC1 P11940 3/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.37
MAOA P21397 3/20 0.35
RAB9A P51151 3/20 0.33
CA2 P00918 1/20 0.33
PTK2B Q14289 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ADORA2A P29274 1/20 0.33
STAT3 P40763 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21880297 0.85 L3MBTL1 (0.67) L3MBTL1MAPTALDH1A1MAPK1TDP1
SCHEMBL26041253 0.84 MAOA (0.46) L3MBTL1MAPTALDH1A1MAPK1TDP1
SCHEMBL26903829 0.83 MAPK1 (0.41) L3MBTL1MAPTALDH1A1MAPK1TDP1
SCHEMBL50547 0.79 ADORA2A (0.52) L3MBTL1MAPTALDH1A1MAPK1TDP1
Anthraquinone SCHEMBL29222026 0.79 ADORA2A (0.52) L3MBTL1MAPTALDH1A1MAPK1TDP1
SCHEMBL26499113 0.76 GABRA1 (0.46) L3MBTL1MAPTALDH1A1MAPK1TDP1
SCHEMBL12445275 0.75 MAPT (0.50) L3MBTL1MAPTALDH1A1MAPK1TDP1
SCHEMBL26043017 0.75 ALDH1A1 (0.40) L3MBTL1MAPTALDH1A1MAPK1TDP1
SCHEMBL12445318 0.72 MEN1 (0.50) L3MBTL1MAPTALDH1A1MAPK1TDP1
SCHEMBL27053386 0.71 MAPT (0.39) L3MBTL1MAPTALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374179-A1 CROSSLINKED POLYMERS AND RELATED COMPOSITIONS, ELECTROCHEMICAL CELLS, BATTERIES, METHODS AND SYSTEMS LINOVA ENERGY INC. 2023-11-23 US disclosed
US-11739173-B2 Crosslinked polymers and related compositions, electrochemical cells, batteries, methods and systems ALIONYX ENERGY SYSTEMS (US) 2023-08-29 US disclosed