SCHEMBL260416

SCHEMBL260416

c1ccn(C2CCCC2)c1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42
DRD3 P35462 1/20 0.42
PKM P14618 1/20 0.36
GAA P10253 2/20 0.35
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 1/20 0.32
SLC18A3 Q16572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601933 0.97 DRD2 (0.41) DRD2DRD4DRD3PKMGAA
SCHEMBL5600054 0.97 DRD2 (0.41) DRD2DRD4DRD3PKMGAA
SCHEMBL5601787 0.97 DRD2 (0.41) DRD2DRD4DRD3PKMGAA
SCHEMBL1901033 0.97 DRD2 (0.41) DRD2DRD4DRD3PKMGAA
SCHEMBL5601758 0.97 DRD2 (0.41) DRD2DRD4DRD3PKMGAA
SCHEMBL5601528 0.97 DRD2 (0.41) DRD2DRD4DRD3PKMGAA
SCHEMBL5599984 0.97 DRD2 (0.41) DRD2DRD4DRD3PKMGAA
SCHEMBL5602242 0.97 DRD2 (0.41) DRD2DRD4DRD3PKMGAA
Hydrochloric Acid SCHEMBL27290402 0.94 DRD2 (0.39) DRD2DRD4DRD3PKMGAA
SCHEMBL5603702 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111655695-B Substituted furopyrimidine compounds as PDE1 inhibitors 达特神经科学有限公司 2025-05-27 CN claimed
CN-118782152-B Organic heterocyclic biomarker for wild and cultivated four-large family fish population and application thereof 中国水产科学研究院长江水产研究所 2025-05-20 CN claimed
CN-118791418-A Indole compound and preparation method and application thereof 纽欧申医药(上海)有限公司 2024-10-18 CN claimed
WO-2024213032-A1 INDOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 纽欧申医药(上海)有限公司 2024-10-17 WO claimed
CN-118782152-A Organic heterocyclic biomarker for wild and cultivated four-large family fish population and application thereof 中国水产科学研究院长江水产研究所 2024-10-15 CN claimed
WO-2024125600-A1 HETEROCYCLIC COMPOUNDS ACTING AS KRAS INHIBITORS, PREPARATION THEREFOR AND THERAPEUTIC USE THEREOF 上海科州药物研发有限公司 2024-06-20 WO claimed
CN-117813306-A Heterocyclic compounds as KRAS inhibitors, their preparation and therapeutic use 上海科州药物研发有限公司 2024-04-02 CN claimed
CN-117586180-A Compounds useful as inhibitors of voltage-gated sodium channels 广州费米子科技有限责任公司 2024-02-23 CN claimed
WO-2024037616-A1 COMPOUND CONTAINING CYCLOHEXYL 正大天晴药业集团股份有限公司 2024-02-22 WO claimed
CN-116332910-A 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof 江苏威凯尔医药科技有限公司 2023-06-27 CN claimed
EP-1720544-B1 NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SERVIER LAB (FR) 2008-03-19 EP claimed
US-20080021031-A1 SELENOPHENE COMPOUNDS NATIONAL HEALTH RESEARCH INSTITUTE (TW) 2008-01-24 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-20070197625-A1 Azabicyclic compounds, a process for their preparation and pharmaceutical compositions containing them. LES LABORATORATIES SERVIER (FR) 2007-08-23 US claimed
WO-2007070046-A1 HALOGEN SUBSTITUTED HETEROATOM-CONTAINING METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-06-21 WO claimed
US-20070135623-A1 Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US claimed
US-5231083-A Cardiovascular disorders and anticoagulants HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-27 US claimed
US-5043346-A Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-27 US claimed
US-4713459-A TRANSFERRING OXYGEN FOR HEMORRHAGE VICTIMS, PRESERVING ORGANS FOR SURGERY THE GREEN CROSS CORPORATION (JP) 1987-12-15 US claimed
US-4558038-A HYPOTENSIVE AGENTS USV PHARMACEUTICAL CORP. (US) 1985-12-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135623-A1 Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization OPRM1, POLM, AP1M1 DRD2 1099/4885DRD4 697/4885DRD3 969/4885
US-20080021031-A1 SELENOPHENE COMPOUNDS CNR2, CNR1, SELENOI DRD2 176/4885DRD4 160/4885DRD3 336/4885
US-20070197625-A1 Azabicyclic compounds, a process for their preparation and pharmaceutical compositions containing them. HRH2, HNMT, HRH1 DRD2 877/4885DRD4 1781/4885DRD3 1934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.