Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1944199 | 0.82 | CYP1A2 (0.55) | L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL14032710 | 0.81 | ESR1 (0.61) | RAB9ASMN1; SMN2CYP19A1 | |
| SCHEMBL21012060 | 0.81 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1HTTPOLBSMN1; SMN2 | |
| SCHEMBL18522503 | 0.81 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1HTTPOLBSMN1; SMN2 | |
| SCHEMBL5177436 | 0.78 | EPHX1 (0.49) | KIF11RAB9ANPC1ALDH1A1HTT | |
| SCHEMBL9502121 | 0.74 | KIF11 (0.39) | KIF11RAB9ANPC1L3MBTL1HRH4 | |
| SCHEMBL22857856 | 0.74 | CYP3A4 (0.39) | HRH4HRH3CYP19A1 | |
| SCHEMBL20968027 | 0.74 | SMN1; SMN2 (0.45) | L3MBTL1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL11396984 | 0.74 | ESR1 (0.48) | RAB9ANPC1TP53TSHRALDH1A1 | |
| SCHEMBL22197081 | 0.73 | KCNA5 (0.43) | L3MBTL1TSHRALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158795-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |