Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21012060 | 1.00 | ALDH1A1 (0.38) | ALDH1A1KDM4ECFTRSLC6A2SLC6A4 | |
| SCHEMBL26046864 | 0.85 | RIPK1 (0.41) | ALDH1A1 | |
| SCHEMBL26042044 | 0.81 | KIF11 (0.49) | ALDH1A1L3MBTL1POLBHTTSMN1; SMN2 | |
| SCHEMBL22857856 | 0.76 | CYP3A4 (0.39) | SLC6A2SLC6A4SLC6A3KCNA5 | |
| SCHEMBL1944199 | 0.76 | CYP1A2 (0.55) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18924481 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KDM4EADRB3POLBSMN1; SMN2 | |
| SCHEMBL20161762 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1KDM4ECFTRSLC6A2SLC6A4 | |
| SCHEMBL14032710 | 0.75 | ESR1 (0.61) | SLC6A2ADRB1ADRB3TBXAS1SMN1; SMN2 | |
| SCHEMBL24467923 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KDM4ECFTRSLC6A2SLC6A4 | |
| SCHEMBL10662943 | 0.72 | L3MBTL1 (0.57) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294252-B2 | Cyclic germanium compounds and applications thereof | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-05-21 | — | — | US | disclosed |
| US-10167299-B2 | 1-(3-aminopropyl) substituted cyclic amine compounds, preparation method therefor, and pharmaceutical compositions and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2019-01-01 | — | — | US | disclosed |
| US-20170044187-A1 | 1-(3-AMINOPROPYL) SUBSTITUTED CYCLIC AMINE COMPOUNDS, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294252-B2 | Cyclic germanium compounds and applications thereof | GMNN, DCX, TRPA1 | ALDH1A1 2258/4885KDM4E 4461/4885CFTR 298/4885 |
| US-20170044187-A1 | 1-(3-AMINOPROPYL) SUBSTITUTED CYCLIC AMINE COMPOUNDS, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | CCR5, CCR1, CCRL2 | ALDH1A1 297/4885KDM4E 1959/4885CFTR 319/4885 |
| US-10167299-B2 | 1-(3-aminopropyl) substituted cyclic amine compounds, preparation method therefor, and pharmaceutical compositions and uses thereof | CCR5, CCRL2, CCR1 | ALDH1A1 823/4885KDM4E 2061/4885CFTR 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.