SCHEMBL1944199

SCHEMBL1944199

CC(Cc1ccccc1)c1cccnc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
CFTR P13569 1/20 0.53
GOPC Q9HD26 1/20 0.53
KDM4E B2RXH2 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 1/20 0.48
TBXAS1 P24557 2/20 0.48
KCNA5 P22460 3/20 0.47
KCNH2 Q12809 2/20 0.47
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
NISCH Q9Y2I1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10662943 0.89 L3MBTL1 (0.57) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL14032710 0.85 ESR1 (0.61) SLC6A2SMN1; SMN2TBXAS1
SCHEMBL20968027 0.83 SMN1; SMN2 (0.45) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22197081 0.82 KCNA5 (0.43) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL26042044 0.82 KIF11 (0.49) SMN1; SMN2L3MBTL1LMNA
SCHEMBL20098043 0.81 CFTR (0.57) CYP2C9CYP2C19SLC6A2SLC6A4SLC6A3
SCHEMBL535702 0.80 TAAR1 (0.56) CYP2D6SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL8983689 0.80 TAAR1 (0.56) CYP2D6SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL14799062 0.80 TAAR1 (0.56) CYP2D6SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL31570749 0.80 L3MBTL1 (0.49) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8334252-B2 Perfume-containing hollow body consisting of a polymer matrix SYMRISE AG (DE) 2012-12-18 US disclosed
US-20110130320-A1 PERFUME-CONTAINING HOLLOW BODY CONSISTING OF A POLYMER MATRIX SYMRISE AG (DE) 2011-06-02 US disclosed