Myrophine

Myrophine

SCHEMBL26043

CCCCCCCCCCCCCC(=O)O[C@H]1C=C[C@H]2[C@H]3Cc4ccc(OCc5ccccc5)c5c4[C@@]2(CCN3C)[C@H]1O5

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 10/20 0.56
OPRM1 P35372 12/20 0.56
OPRK1 P41145 10/20 0.56
MRGPRX2 Q96LB1 2/20 0.51
ADRB1 P08588 1/20 0.50
PDE4D Q08499 1/20 0.50
PDE3A Q14432 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Myrophine SCHEMBL29851007 1.00 OPRD1 (0.56) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL3477477 0.89 OPRM1 (0.71) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL7775794 0.89 OPRM1 (0.71) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL7770909 0.89 OPRM1 (0.71) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL3477727 0.86 OPRM1 (0.73) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL29610430 0.85 OPRM1 (0.77) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL22959877 0.85 OPRM1 (0.77) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL3477203 0.84 OPRM1 (0.70) OPRD1OPRM1OPRK1MRGPRX2ADRB1
SCHEMBL8208039 0.83 OPRM1 (0.62) OPRD1OPRM1OPRK1
SCHEMBL19463540 0.83 OPRD1 (0.72) OPRD1OPRM1OPRK1MRGPRX2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6219 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
US-20250228771-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-07-17 US claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP claimed
EP-4565202-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-06-11 EP claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 WO claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
US-20240288374-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation 2024-08-29 US claimed
WO-2024172892-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation (US) 2024-08-22 WO claimed
US-5958452-A SUSTAINED RELEASE FORMULATION COMPRISING EXTRUDED BLEND OF DRUG, HYDROPHOBIC MATERIAL, HYDROPHOBIC FUSIBLE CARRIER DIVIDED INTO UNIT DOSE EURO-CELTIQUE, S.A. (LU) 1999-09-28 US claimed
WO-1999013799-A1 SYNERGISTIC ANALGESIC COMBINATION OF OPIOID ANALGESIC AND CYCLOOXYGENASE-2 INHIBITOR EURO-CELTIQUE, S.A. (LU) 1999-03-25 WO claimed
EP-0785775-A4 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO CELTIQUE SA (LU) 1998-08-19 EP claimed
EP-0785775-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS Euroceltique S.A. (LU) 1997-07-30 EP claimed
EP-0731694-A4 1996-10-02 EP claimed
EP-0731694-A1 OPIOID FORMULATIONS FOR TREATING PAIN Euroceltique S.A. (LU) 1996-09-18 EP claimed
CN-1130352-A Method for relieving pain by orally administering 24-hour sustained-release opioid dosage form capable of rapidly increasing initial blood concentration of patient EURO CELTIQUE SA (LU) 1996-09-04 CN claimed
WO-1996014058-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO-CELTIQUE, S.A. (LU) 1996-05-17 WO claimed
WO-1995014460-A1 OPIOID FORMULATIONS FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 1995-06-01 WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 EP claimed