Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | PNKP | Q96T60 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29052458 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MGLLHDAC3HDAC1HDAC2 | |
| SCHEMBL29051938 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MGLLHDAC3HDAC1HDAC2 | |
| SCHEMBL1142097 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MGLLHDAC3HDAC1HDAC2 | |
| SCHEMBL17941247 | 0.99 | ALDH1A1 (0.50) | ALDH1A1MGLLHDAC3HDAC1HDAC2 | |
| SCHEMBL25612582 | 0.95 | HDAC3 (0.49) | ALDH1A1MGLLHDAC3HDAC1HDAC2 | |
| SCHEMBL1704751 | 0.87 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1MAPTTSHRKMT2A | |
| SCHEMBL12537417 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MGLLHDAC3HDAC1HDAC2 | |
| SCHEMBL9979054 | 0.84 | PRKCA (0.50) | ALDH1A1MGLLHDAC3HDAC1HDAC2 | |
| SCHEMBL28344393 | 0.84 | ADRB2 (0.50) | ALDH1A1ADRB2ADRB1ADRB3MAPT | |
| SCHEMBL14273580 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2112136-B1 | BIS(2-ALKOXYETHYL) AZODICARBOXYLATE ESTER COMPOUND AND INTERMEDIATE FOR PRODUCTION OF THE SAME | TOYO BOSEKI (JP) | 2012-05-23 | — | — | EP | disclosed |
| US-8067440-B2 | Phosphonium salts derivatives and uses thereof | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-11-29 | — | — | US | disclosed |
| US-7947816-B2 | Azodicarboxylic acid bis(2-alkoxyethyl) ester compound, and production intermediate thereof | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-04-21 | — | — | US | disclosed |
| US-20110028701-A1 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF | TOYOBO MC CORPORATION (JP) | 2011-02-03 | — | — | US | disclosed |
| US-7880037-B2 | Phosphonium supported triphenylphosphine; for controlling solubility of a molecule; oxidation of Cinnamyl Alcohol using above catalyst system | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-02-01 | — | — | US | disclosed |
| US-7880037-B2 | Phosphonium supported triphenylphosphine; for controlling solubility of a molecule; oxidation of Cinnamyl Alcohol using above catalyst system | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-02-01 | — | — | US | disclosed |
| US-7820802-B2 | Azodicarboxylic acid bis(2-alkoxyethyl) ester compound, and production intermediate thereof | TOYOBO MC CORPORATION (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20100048881-A1 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF | TOYO KASEI KOGYO CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2112136-A1 | BIS(2-ALKOXYETHYL) AZODICARBOXYLATE ESTER COMPOUND AND INTERMEDIATE FOR PRODUCTION OF THE SAME | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2009-10-28 | — | — | EP | disclosed |
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | VALORISATION-RECHERECHE (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | VALORISATION-RECHERECHE (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028701-A1 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF | CPS1, MCCC2, PC | ALDH1A1 554/4885MGLL 1857/4885HDAC3 3160/4885 |
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | PI4K2A, PIP4K2A, PI4K2B | ALDH1A1 3806/4885MGLL 4756/4885HDAC3 2399/4885 |
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | PI4K2A, PIP4K2A, PI4K2B | ALDH1A1 3468/4885MGLL 4589/4885HDAC3 2586/4885 |
| US-20100048881-A1 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF | CPS1, MCCC2, PC | ALDH1A1 554/4885MGLL 1857/4885HDAC3 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.