SCHEMBL260456

SCHEMBL260456

CCCC(O)C(O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.52
AKR1A1 P14550 1/20 0.52
CHRM3 P20309 1/20 0.52
HTR2A P28223 1/20 0.52
HTR2C P28335 1/20 0.52
ADRA1A P35348 1/20 0.52
HRH1 P35367 1/20 0.52
DRD3 P35462 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC2 Q92769 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TSHR P16473 3/20 0.45
GPR84 Q9NQS5 3/20 0.43
FFAR1 O14842 1/20 0.43
LMNA P02545 1/20 0.41
PDE4A P27815 1/20 0.41
PGD P52209 1/20 0.40
GRIK1 P39086 1/20 0.40
SLC1A3 P43003 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10535143 1.00 CHRM1 (0.52) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL10535132 1.00 CHRM1 (0.52) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL17984930 0.85 PDE4A (0.48) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL7050623 0.85 CA2 (0.52) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL7080439 0.83 GPR84 (0.59) GPR84FFAR1LMNAGRIK1SLC1A2
SCHEMBL7076752 0.81 GPR84 (0.63) GPR84FFAR1LMNACYP3A4
SCHEMBL7080657 0.81 GPR84 (0.63) GPR84FFAR1LMNACYP3A4
SCHEMBL7083858 0.81 GPR84 (0.63) GPR84FFAR1LMNACYP3A4
SCHEMBL5703592 0.81 GPR84 (0.63) GPR84FFAR1LMNACYP3A4
SCHEMBL3629168 0.81 GPR84 (0.63) GPR84FFAR1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113759065-B Method for simultaneously identifying components of coptis chinensis and phellodendron amurense and application of method 北京康仁堂药业有限公司 2023-04-07 CN claimed
CN-113759065-A Method for simultaneously identifying components of coptis chinensis and phellodendron amurense and application of method 北京康仁堂药业有限公司 2021-12-07 CN claimed
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2012-02-16 US claimed
EP-1981831-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF Vaidya, Niteen A. (US) 2008-10-22 EP claimed
WO-2007092264-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2007-08-16 WO claimed
US-20070185346-A1 Kit for automated resolving agent selection and method thereof VAIDYA NITEEN A 2007-08-09 US claimed
WO-2005052042-A2 MIXTURES OF HYDROFLUORCARBONS AND ACIDS AS FOAM BLOWING AGENTS HONEYWELL INTERNATIONAL INC. (US) 2005-06-09 WO claimed
US-20050113470-A1 Mixtures of hydrofluorcarbons and acids as foam blowing agents HONEYWELL CORPORATION 2005-05-26 US claimed
US-20250127925-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2025-04-24 US disclosed
US-12076418-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo ENGENE, INC. (CA) 2024-09-03 US disclosed
CN-113759065-B Method for simultaneously identifying components of coptis chinensis and phellodendron amurense and application of method 北京康仁堂药业有限公司 2023-04-07 CN disclosed
CN-113759065-B Method for simultaneously identifying components of coptis chinensis and phellodendron amurense and application of method 北京康仁堂药业有限公司 2023-04-07 CN disclosed
US-20220133907-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO HERCULES CAPITAL, INC. 2022-05-05 US disclosed
EP-3970697-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO Engene, Inc. (CA) 2022-03-23 EP disclosed
US-4128540-A Pyroglutamyl-histidyl-tryptophanyl-seryl-tyrosyl hydrazides PARKE, DAVIS & COMPANY (US) 1978-12-05 US disclosed
US-4124578-A ANTIFERTILITY AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-11-07 US disclosed
US-4113442-A C 10-40 HYDROCARBYL ESTER OF HYDROXYCARBOXYLIC ACID AS FILTERABILITY IMPROBER SHELL OIL COMPANY (US) 1978-09-12 US disclosed
US-4011207-A Des-(Ala1, Gly2,Lys4 -Srif, Des-(Ala1, Gly2, Lys4)-D-Trp8 -Srif and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-08 US disclosed
US-3948885-A ANTIVIRAL ICN PHARMACEUTICALS, INC. (US) 1976-04-06 US disclosed
US-3931140-A (H-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127925-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP CHRM1 4789/4885AKR1A1 2947/4885CHRM3 4693/4885
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF ACKR3, KIT, C3AR1 CHRM1 2560/4885AKR1A1 20/4885CHRM3 1377/4885
US-12076418-B2 Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo CSGALNACT1, CHI3L2, LNPEP CHRM1 4789/4885AKR1A1 2947/4885CHRM3 4693/4885
US-20220133907-A1 DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO CSGALNACT1, CHI3L2, LNPEP CHRM1 4789/4885AKR1A1 2947/4885CHRM3 4693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.