SCHEMBL2604686

SCHEMBL2604686

C=C(F)C(=O)Oc1ccc2c(c1)C(C)c1cc(OC(=O)C(=C)F)ccc1-2

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
ELANE P08246 1/20 0.33
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
OPRM1 P35372 1/20 0.30
ACHE P22303 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2125191 0.86 ELANE (0.46) HTR7HTR2BELANELMNAKMT2A
SCHEMBL21266322 0.85 HSD17B10 (0.35) HTR7HTR2BELANEGAAKMT2A
SCHEMBL2606426 0.84 LMNA (0.36) HTR7HTR2BELANELMNAGAA
SCHEMBL23082336 0.82 MAPT (0.33) HTR7HTR2BELANEKMT2A
SCHEMBL2604688 0.79 ELANE (0.39) ELANELMNAGAAKMT2AATM
SCHEMBL21266153 0.78 KMT2A (0.37) LMNAGAAKMT2A
SCHEMBL6536369 0.78 LMNA (0.47) ELANELMNAGAAKMT2AOPRM1
SCHEMBL22596883 0.78 ALDH1A1 (0.31) LMNA
SCHEMBL2122679 0.78 THRB (0.45) HTR7HTR2BLMNAKMT2AOPRM1
SCHEMBL14088598 0.77 HTT (0.47) LMNAGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394468-B2 Polymerizable compound and liquid crystal composition including it JNC CORPORATION (JP) 2013-03-12 US disclosed
US-8394468-B2 Polymerizable compound and liquid crystal composition including it JNC CORPORATION (JP) 2013-03-12 US disclosed
US-20120092608-A1 POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL COMPOSITION INCLUDING IT JNC PETROCHEMICAL CORPORATION (JP) 2012-04-19 US disclosed
US-20120092608-A1 POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL COMPOSITION INCLUDING IT JNC PETROCHEMICAL CORPORATION (JP) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120092608-A1 POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL COMPOSITION INCLUDING IT KLK3, PDE7A, FZD7 HTR7 142/4885HTR2B 1352/4885ELANE 2411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.