Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.43 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015859 | 0.93 | HDAC8 (0.62) | HDAC8ALDH1A1HPGDHTTKDM4E | |
| SCHEMBL21957672 | 0.83 | HDAC8 (0.58) | HDAC8ALDH1A1KDM4EAPPMAOB | |
| SCHEMBL26047483 | 0.81 | HDAC8 (0.50) | HDAC8ALDH1A1HPGDMAOBMAPT | |
| SCHEMBL30970368 | 0.78 | ABCG2 (0.45) | ALDH1A1HPGDKDM4EAPPMAPT | |
| SCHEMBL5524484 | 0.77 | HDAC8 (0.58) | HDAC8ALDH1A1KDM4EAPPMAOB | |
| SCHEMBL5524486 | 0.77 | HDAC8 (0.58) | HDAC8ALDH1A1KDM4EAPPMAOB | |
| SCHEMBL1884913 | 0.77 | CA12 (0.62) | HDAC8MAPTCA12CA4CA6 | |
| SCHEMBL1884911 | 0.77 | CA12 (0.62) | HDAC8MAPTCA12CA4CA6 | |
| SCHEMBL18559977 | 0.76 | HDAC8 (0.69) | HDAC8ALDH1A1HTTKDM4EAPP | |
| SCHEMBL21957648 | 0.76 | HDAC8 (0.54) | HDAC8MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11690810-B2 | Combination treatment of bacterial infection | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11690810-B2 | Combination treatment of bacterial infection | PGC, NRDC, PYCARD | HDAC8 241/4885ALDH1A1 3345/4885HPGD 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.