SCHEMBL2604844

SCHEMBL2604844

CC(C)c1nc2ccccc2n1-c1ccc(-c2c3ccccc3c(-c3ccc(-c4cccc5ccccc45)cc3)c3ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.45
CRBN Q96SW2 1/20 0.43
PIK3CD O00329 1/20 0.40
PIK3CA P42336 1/20 0.40
PIK3CB P42338 1/20 0.40
PIK3CG P48736 1/20 0.40
FLT3 P36888 3/20 0.39
PDE10A Q9Y233 2/20 0.39
CYP1A2 P05177 1/20 0.39
PPARG P37231 5/20 0.37
PPARA Q07869 5/20 0.37
BMX P51813 2/20 0.36
LMNA P02545 1/20 0.36
ENPP3 O14638 1/20 0.36
ENPP1 P22413 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2604826 0.95 CNR2 (0.45) CNR2CRBNPIK3CDPIK3CAPIK3CB
SCHEMBL14499583 0.89 PDE10A (0.40) CNR2CRBNPDE10ACYP1A2PPARG
SCHEMBL2604827 0.88 CRBN (0.43) CNR2CRBNPIK3CDPIK3CAPIK3CB
SCHEMBL2604845 0.87 CRBN (0.43) CNR2CRBNPIK3CDPIK3CAPIK3CB
SCHEMBL2604846 0.87 CRBN (0.47) CNR2CRBNPIK3CDPIK3CAPIK3CB
SCHEMBL2604828 0.87 CRBN (0.47) CNR2CRBNPIK3CDPIK3CAPIK3CB
SCHEMBL2604825 0.86 CRBN (0.47) CNR2CRBNPIK3CDPIK3CAPIK3CB
SCHEMBL2604838 0.85 CRBN (0.47) CNR2CRBNPIK3CDPIK3CAPIK3CB
SCHEMBL2604832 0.84 MAPK1 (0.55) FLT3BMXLMNAENPP3ENPP1
SCHEMBL12912429 0.83 CRBN (0.43) CNR2CRBNPIK3CDPIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-20120091438-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-04-19 US disclosed
US-20120091438-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-04-19 US disclosed
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-21 US disclosed
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 CNR2 4512/4885CRBN 4069/4885PIK3CD 3449/4885
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME EHD1, HCN2, ODC1 CNR2 2423/4885CRBN 3471/4885PIK3CD 1266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.