SCHEMBL26048690

SCHEMBL26048690

CC(C)(C)OC(=O)[N+]1(C)CC(C2CNC2)C1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 8/20 0.33
CHRNA4 P43681 8/20 0.33
CHRNB4 P30926 7/20 0.33
CHRNA3 P32297 7/20 0.33
CHRNA7 P36544 6/20 0.33
CCR5 P51681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26974149 0.77 NFKB1 (0.32)
SCHEMBL25962672 0.74 NFKB1 (0.31)
SCHEMBL26048597 0.71 MEN1 (0.31)
SCHEMBL26707334 0.71 CHRM2 (0.30)
SCHEMBL2838003 0.71 CHRM2 (0.30)
SCHEMBL28029280 0.70 NR1H2 (0.33)
SCHEMBL26049353 0.69 CYP1A2 (0.31)
SCHEMBL14896297 0.67 DGAT1 (0.32)
SCHEMBL3790678 0.67
SCHEMBL24815923 0.67 CHRNB2 (0.58) CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023163712-A1 MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN NALO THERAPEUTICS (US) 2023-08-31 WO disclosed
WO-2023164611-A1 MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN NALO THERAPEUTICS (US) 2023-08-31 WO disclosed