Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25962672 | 0.83 | NFKB1 (0.31) | NFKB1NFKB2RELAMAPK1 | |
| SCHEMBL26048690 | 0.77 | CHRNB2 (0.33) | — | |
| SCHEMBL27273077 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL25473022 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL7965908 | 0.71 | NFKB1 (0.32) | NFKB1NFKB2RELAMAPK1GAA | |
| SCHEMBL26048597 | 0.69 | MEN1 (0.31) | MAPK1 | |
| SCHEMBL14896297 | 0.69 | DGAT1 (0.32) | — | |
| SCHEMBL28029280 | 0.68 | NR1H2 (0.33) | — | |
| SCHEMBL27459045 | 0.67 | CHRM2 (0.43) | — | |
| SCHEMBL13727442 | 0.66 | NR1H2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858939-B2 | Hetero-halo inhibitors of histone deacetylase | ALKERMES, INC. (US) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858939-B2 | Hetero-halo inhibitors of histone deacetylase | HDAC2, HDAC1, HDAC6 | NFKB1 1228/4885NFKB2 681/4885RELA 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.