Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26052184 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2FFAR1MAPK14PPARGROCK1 | |
| SCHEMBL26052060 | 0.84 | ROCK2 (0.43) | MAPK14ROCK1ROCK2ALDH1A1KMT2A | |
| SCHEMBL26050634 | 0.83 | MAOA (0.43) | SMN1; SMN2ROCK2MCHR1 | |
| SCHEMBL25370158 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2FFAR1MAPK14PPARGROCK1 | |
| SCHEMBL30580188 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2FFAR1MAPK14PPARGROCK1 | |
| SCHEMBL26052062 | 0.79 | EPHX2 (0.36) | MEN1LMNAKMT2AMCHR1 | |
| SCHEMBL26052061 | 0.78 | EPHX2 (0.36) | MCHR1 | |
| SCHEMBL26051600 | 0.78 | EPHX2 (0.36) | MCHR1 | |
| SCHEMBL26051813 | 0.74 | MAPK14 (0.50) | MAPK14ROCK1ROCK2CACNA1GCACNA1H | |
| SCHEMBL26050993 | 0.73 | MAPK14 (0.49) | MAPK14PPARGROCK1ROCK2CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158584-A1 | NEW BICYCLOPENTANE DERIVATIVES | ICAGEN, LLC (US) | 2023-08-24 | — | — | WO | disclosed |