Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 2/20 | 0.40 |
| ▸ | CLPP | Q16740 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | GLMN | Q92990 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26052062 | 0.89 | EPHX2 (0.36) | MAOAERCC1ERCC4MCHR1 | |
| SCHEMBL26051934 | 0.84 | ERCC1 (0.46) | MAOAERCC1ERCC4SMN1; SMN2NAMPT | |
| SCHEMBL26050757 | 0.83 | MAOA (0.43) | MAOAERCC1ERCC4SMN1; SMN2NAMPT | |
| SCHEMBL26052184 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2MCHR1ROCK2 | |
| SCHEMBL26051696 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2MCHR1ROCK2 | |
| SCHEMBL26051600 | 0.82 | EPHX2 (0.36) | MCHR1 | |
| SCHEMBL26052061 | 0.82 | EPHX2 (0.36) | MCHR1 | |
| SCHEMBL26052060 | 0.80 | ROCK2 (0.43) | ROCK2 | |
| SCHEMBL26051867 | 0.79 | MAOA (0.48) | MAOAERCC1ERCC4SMN1; SMN2NAMPT | |
| SCHEMBL26050994 | 0.78 | P2RX7 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158584-A1 | NEW BICYCLOPENTANE DERIVATIVES | ICAGEN, LLC (US) | 2023-08-24 | — | — | WO | disclosed |